Shipping to United States We Offer Worldwide Shipping
Login Wishlist

Vanillyl alcohol

$45

  • Brand : BIOFRON

  • Catalogue Number : AV-P12376

  • Specification : 98%

  • CAS number : 498-00-0

  • Formula : C8H10O3

  • Molecular Weight : 154.16

  • PUBCHEM ID : 62348

  • Volume : 100mg

Available on backorder

Quantity
Checkout Bulk Order?

Catalogue Number

AV-P12376

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

154.16

Appearance

White powder

Botanical Source

Vanillaplanifolia Andr.

Structure Type

Simple Phenolic Compounds

Category

Standards;Natural Pytochemical;API

SMILES

COC1=C(C=CC(=C1)CO)O

Synonyms

4-Hydroxy-3-methoxybenzyl alcohol/Vanillyl alcohol/Benzenemethanol, 4-hydroxy-3-methoxy-/4-(Hydroxymethyl)-2-methoxyphenol

IUPAC Name

4-(hydroxymethyl)-2-methoxyphenol

Applications

Vanillyl alcohol (Vanillic alcohol), derived from vanillin, is a phenolic alcohol and is used as a flavoring agent in foods and beverages[1].

Density

1.2±0.1 g/cm3

Solubility

Methanol

Flash Point

143.2±23.7 °C

Boiling Point

313.1±27.0 °C at 760 mmHg

Melting Point

110-117 °C(lit.)

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:498-00-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

21705974

Abstract

Gastrodia elata Blume (GE) has long been used in oriental countries as a traditional herbal medicine to relieve symptoms associated with neurological ailments such as vertigo, general paralysis and epilepsy. In this study, we have investigated the effects of GE extracts and its major bioactive components on 1-methyl-4-phenylpyridinium (MPP+)-treated MN9D dopaminergic cells, a classic in vitro model for Parkinson’s disease (PD). We found that vanillyl alcohol effectively inhibited the cytotoxicity and improved cell viability in MPP+-induced MN9D dopaminergic cells. The underlying mechanisms of vanillyl alcohol action were also studied. Vanillyl alcohol attenuated the elevation of reactive oxygen species (ROS) levels, decreased in the Bax/Bcl-2 ratio and poly (ADP-ribose) polymerase proteolysis. These results indicate that vanillyl alcohol protected dopaminergic MN9D cells against MPP+-induced apoptosis by relieving oxidative stress and modulating the apoptotic process and is therefore a potential candidate for treatment of neurodegenerative diseases such as Parkinson’s disease.

Title

Neuroprotective effects of vanillyl alcohol in Gastrodia elata Blume through suppression of oxidative stress and anti-apoptotic activity in toxin-induced dopaminergic MN9D cells.

Author

Kim IS1, Choi DK, Jung HJ.

Publish date

2011 Jun 24

PMID

18958417

Abstract

Vanillyl alcohol displayed a significant inhibition in the chick chorioallantoic membrane (CAM) angiogenesis. Vanillyl alcohol was also shown to contain anti-inflammatory activity using acetic acid-induced permeability and carrageenan-induced air pouch models in mice. Anti-nociceptive activity of vanillyl alcohol was also assessed using acetic acid-induced writhing test in mice. Taken together, vanillyl alcohol possesses anti-angiogenic, anti-inflammatory, and anti-nociceptive activities, which may be partly responsible for pharmacological efficacies of several folkloric medicines containing vanillyl alcohol.

Title

Anti-angiogenic, anti-inflammatory and anti-nociceptive activities of vanillyl alcohol.

Author

Jung HJ1, Song YS, Lim CJ, Park EH.

Publish date

2008 Oct

PMID

15844340

Abstract

The electrooxidation of benzylic alcohol derivative in acidic aqueous solution shows an oxidation pre-peak in the cyclic voltammogram, which means that the reaction is proceeding via an ECE mechanism where the second electron transfer occurs at a less positive potential. From the result of the rotating ring-disk electrode voltammetry, the initial oxidation response of the electrode reaction can be extracted.

Title

Electrooxidation of vanillyl alcohol in acidic aqueous solution using rotating ring-disk electrode voltammetry.

Author

Kishioka SY1, Yamada A.

Publish date

2005 Apr