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Visnadin

$3,600

  • Brand : BIOFRON

  • Catalogue Number : BN-O1856

  • Specification : 98%(HPLC)

  • CAS number : 477-32-7

  • Formula : C21H24O7

  • Molecular Weight : 388.4

  • PUBCHEM ID : 442151

  • Volume : 20mg

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Catalogue Number

BN-O1856

Analysis Method

Specification

98%(HPLC)

Storage

2-8°C

Molecular Weight

388.4

Appearance

Botanical Source

Structure Type

Category

SMILES

Synonyms

IUPAC Name

[(9R,10R)-10-acetyloxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl] (2R)-2-methylbutanoate

Applications

Density

1.3±0.1 g/cm3

Solubility

Flash Point

206.9±28.8 °C

Boiling Point

477.7±45.0 °C at 760 mmHg

Melting Point

InChl

InChl Key

GVBNSPFBYXGREE-CXWAGAITSA-N

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:477-32-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

31698889

Abstract

Background: There is a growing interest on women’ sexual function improvement provided by topical vulvar application of Visnadine, a natural extractive substance with putative vasodilatory properties. Aims of this study were to evaluate: 1) the vasokinetic activity of a Visnadine Emulgel on mucosal genitalia of 15 healthy postmenopausal women clinically and by instrumental non-invasive analysis; 2) the treatment efficacy by volunteers’ judgment regarding to subjective comfort, pleasant warmth, lubrication grade, pinching and burning vulvar sensations.

Methods: Fifteen informed healthy female volunteers with menopause were enrolled in the study, with a single blind controlled study versus placebo corresponding to one single application of the emulgel product (active or placebo) on external genitalia.

Results: Visnadine Emulgel single application determined a significant increase of vulvar hyperemia, evaluated both clinically and instrumentally, accompanied by a significant increase of local turgor versus placebo. The volunteers reported a pleasant comfort sensation.

Conclusions: The topical use of Visnadine on female external genitalia may increase regional vascularization affecting turgidity and sensorial threshold of the area of application.

Title

A randomized single-blind placebo-controlled study of a Visnadine Emulgel formulation on healthy postmenopausal women

Author

Adele Sparavigna 1, Alberto Caputo 2, Alice Natoli 3, Clara Mandelli 4

Publish date

2019 Oct;

PMID

29952501

Title

Efficacy of an intimate oil solution containing visnadine in women self-reporting sexual symptoms

Author

Alberto Caputo 1, Alice Natoli 1, Rossella Radice 2, Gabriele Zanardi 3, Luca Giacomelli 4

Publish date

2018 Aug;

PMID

29452786

Abstract

This single-arm pilot study enrolled 47 post-menopausal women affected by vulvovaginal atrophy (VVA). The Vaginal Health Index Score (VHIS) was evaluated for all women and all completed the Female Sexual Function Index (FSFI) questionnaire at baseline (T0) and after 15 days of vaginal cream treatment with one application per day (T1). Following treatment there was a significant improvement in all VHIS parameters and total score (p < 0.0001). Similarly, there was a significant improvement on four FSFI domains (lubrication, orgasm, satisfaction and pain) and total score (p = 0.001). None of the patients reported any local or systemic side-effects during treatment.

KEYWORDS

Bovine colostrum; Menopause; Prenylflavonoids; Sexual wellbeing; Visnadine; Vulvovaginal atrophy.

Title

Preliminary results of a single-arm pilot study to assess the safety and efficacy of visnadine, prenylflavonoids and bovine colostrum in postmenopausal sexually active women affected by vulvovaginal atrophy

Author

Antonio Simone Laganà 1, Salvatore Giovanni Vitale 2, Lily Stojanovska 3, Irene Lambrinoudaki 4, Vasso Apostolopoulos 3, Benito Chiofalo 2, Laura Rizzo 2, Francesca Basile 2

Publish date

2018 Mar;