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Vitamin B6

$70

Brand : BIOFRON
Catalogue Number : BN-O0008
Specification : 98%(HPLC)
CAS number : 8059-24-3
Formula : C8H10NO5P-2
Molecular Weight : 231.14
PUBCHEM ID : 104817
Volume : 20mg

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Catalogue Number

BN-O0008

Analysis Method

Specification

98%(HPLC)

Storage

2-8°C

Molecular Weight

231.14

Appearance

Botanical Source

Structure Type

Category

SMILES

CC1=C(C(=NC=C1COP(=O)([O-])[O-])C)O

Synonyms

(5-Hydroxy-4,6-dimethylpyridin-3-yl)methyl phosphate/3-Pyridinemethanol, 5-hydroxy-4,6-dimethyl-, α-(dihydrogen phosphate), ion(2-)/(5-Hydroxy-4,6-dimethyl-3-pyridinyl)methyl phosphate

IUPAC Name

(5-hydroxy-4,6-dimethylpyridin-3-yl)methyl phosphate

Density

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

297.1±32.9 °C

Boiling Point

567.6±60.0 °C at 760 mmHg

Melting Point

231-233ºC(lit.)

InChl

InChl Key

RBCOYOYDYNXAFA-UHFFFAOYSA-L

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:8059-24-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

31800708

Abstract

Sepsis is a life-threatening organ dysfunction induced by a disrupted host response to infecting pathogens. Inflammation and oxidative stress are intrinsically related to sepsis progression and organ failure. Vitamin B6 is an important cellular cofactor for metabolic processes and has anti-inflammatory and antioxidant properties. We aimed at evaluating the effect of vit B6 on inflammation and oxidative stress markers in the liver and lung of rats subjected to a relevant animal model of polymicrobial sepsis. Adult male Wistar rats were submitted to cecal ligation and perforation model and immediately after sepsis induction, vit B6 was administered as a single dose (600 mg/kg, subcutaneous). Twenty-four hours later, the lung and liver were harvest for neutrophil infiltration, oxidative markers to lipids and protein and antioxidant activity of endogenous enzyme. Vitamin B6 diminished neutrophil infiltration in both organs, oxidative markers in the liver and restored catalase activity levels in the lung of septic animals. Vitamin B6 exerts anti-inflammatory and antioxidant effects in peripheral organs after polymicrobial sepsis.

Title

Vitamin B6 reduces oxidative stress in lungs and liver in experimental sepsis.

Author

Giustina AD1, Danielski LG1, Novochadlo MM1, Goldim MPS1, Joaquim L1, Metzker KLL1, Carli RJ1, Denicol T1, Cidreira T1, Vieira T1, Petronilho F1.

Publish date

2019 Dec 2

PMID

31514825

Abstract

Raman spectroelectrochemistry based on electrochemical surface-enhanced Raman scattering (EC-SERS) effect is an interesting alternative to overcome the lack of sensitivity of normal Raman spectroscopy. Electrochemical activation of metallic screen-printed electrodes (SPEs) leads to the reproducible generation of nanostructures with excellent SERS properties. In that way, gold SPEs circumvent the traditional reproducibility limitation and produce the enhancement of the Raman intensity to favor the detection of low concentrations. Furthermore, fingerprint features of Raman spectroscopy make possible the dynamic spectroelectrochemical analysis of B vitamins. The accuracy assignments of Raman bands associated with B1, B2, B3, B6 and B12 vitamins present in multivitamin complexes provides valuable information, allowing us not only the detection of B vitamin present in mixtures, but also to understand the interaction between vitamins and metallic SERS surfaces.

Copyright © 2019 Elsevier B.V. All rights reserved.

KEYWORDS

B vitamins; EC-SERS; Multivitamin complexes; Raman spectroelectrochemistry; Screen-printed electrodes (SPEs)

Title

Spectroelectrochemical elucidation of B vitamins present in multivitamin complexes by EC-SERS.

Author

IbaNez D1, Perez-Junquera A2, Gonzalez-Garcia MB2, Hernandez-Santos D2, Fanjul-Bolado P3.

Publish date

2020 Jan 1

PMID

31513285

Abstract

The impacts of thiamin and pyridoxine along with YAN on alcoholic fermentation and hydrogen sulphide production by Saccharomyces cerevisiae were studied. Using a synthetic grape juice medium, three fermentation trials were conducted; (i) 2 × 3 factorial design with thiamin (0, 0·2, or 0·5 mg l-1 ) and YAN (60 or 250 mg l-1 ) as variables, (ii) 2 × 3 factorial design with pyridoxine (0, 0·25, or 0·5 mg l-1 ) and YAN (60 or 250 mg l-1 ) as variables, and (iii) 3 × 3 factorial design with thiamin (0, 0·2 or 0·5 mg l-1 ) and pyridoxine (0, 0·25 or 0·5 mg l-1 ) as variables in media containing 60 mg l-1 YAN. Although the progress of fermentations was affected by thiamin or pyridoxine, YAN had a larger impact than either vitamin. H2 S production was significantly lower with increasing amounts of thiamin in those fermentations under low YAN (60 mg l-1 ) while even lower amounts (<30 µg l-1 ) were produced under high YAN (250 mg l-1 ) with or without the vitamin. The highest amounts of H2 S were synthesized in those fermentations without any pyridoxine (>110 µg l-1 ), with the lowest production in media with pyridoxine and high YAN (<20 µg l-1 ). SIGNIFICANCE AND IMPACT OF THE STUDY: Concentrations of thiamin, pyridoxine and yeast assimilable nitrogen (YAN) influenced the synthesis of hydrogen sulphide (H2 S) by Saccharomyces cerevisiae in a synthetic grape juice medium. With a few exceptions, an increase in the concentration of either vitamin or YAN resulted in less H2 S released. This is the first report to demonstrate that both thiamin and pyridoxine along with YAN affected H2 S production, emphasizing the need to assess yeast nutrients to lower risks of off-odours during fermentation. © 2019 The Society for Applied Microbiology.

KEYWORDS

H2S; alcoholic; fermentation; pyridoxine; thiamin

Title

Hydrogen sulphide production by Saccharomyces cerevisiae UCD 522 in a synthetic grape juice medium deficient of thiamin (vitamin B1 ) and/or pyridoxine (vitamin B6 ).

Author

Xing H1, Edwards CG1.

Publish date

2019 Nov